Ligusticum Chuanxiong Extract

INCI: LIGUSTICUM CHUANXIONG EXTRACT (WHOLE PLANT); ALSO REGISTERED AS LIGUSTICUM CHUANXIONG ROOT EXTRACT (ROOT-SPECIFIC)

CAS Number
4431-01-0 (referenced for the root extract variant)
Function
Skin conditioning (whole-plant extract); hair conditioning + skin conditioning (root extract)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition; subject to general safety requirements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains bioactive alkaloids (ligustrazine/tetramethylpyrazine), ferulic acid, and ligustilide. May have blood-thinning properties; interactions possible with anticoagulants. Easy to oxidize - requires proper storage. Derived from Sichuan Lovage (Ligusticum chuanxiong, Apiaceae), a cornerstone of Traditional Chinese Medicine known as "Chuanxiong." Stimulates microcirculation, improves skin tone, moisturizes, and tones skin. Also demonstrates antithrombotic activity and smooth-muscle relaxatio...

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Ligusticum Chuanxiong Extract safe in cosmetics?

Contains bioactive alkaloids (ligustrazine/tetramethylpyrazine), ferulic acid, and ligustilide. May have blood-thinning properties; interactions possible with anticoagulants. Easy to oxidize - requires proper storage. Derived from Sichuan Lovage (Ligusticum chuanxiong, Apiaceae), a cornerstone of Traditional Chinese Medicine known as "Chuanxiong." Stimulates microcirculation, improves skin tone, moisturizes, and tones skin. Also demonstrates antithrombotic activity and smooth-muscle relaxatio... The EU classifies Ligusticum Chuanxiong Extract as "permitted". Safety rating: MODERATE.

Is Ligusticum Chuanxiong Extract allowed in the EU?

Ligusticum Chuanxiong Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ligusticum Chuanxiong Extract do in cosmetics?

Ligusticum Chuanxiong Extract functions as: Skin conditioning (whole-plant extract); hair conditioning + skin conditioning (root extract). It is classified as a cosmetic ingredient in our database. CAS number: 4431-01-0 (referenced for the root extract variant).

What is the Margin of Safety for Ligusticum Chuanxiong Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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