Lithium Hydroxide

INCI: LITHIUM HYDROXIDE

CAS Number
1310-65-2 [^1_5]
Function
Buffering / pH adjuster / hair straightening / depilatory agent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR prohibition; used in 16 US cosmetic products (2011 PCPC data)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Corrosive (Cat. 1B, H314); causes severe skin burns and eye damage; dermal LD50 200โ€“3000 mg/kg bw in rabbits with total skin destruction at high dose; must never exceed regulatory pH/concentration limits; professional-use-only designation required above 2%; acute lithium systemic toxicity possible via damaged skin

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Concern Level: High

Regulatory Flags

endocrine_disruptor

Frequently Asked Questions

Is Lithium Hydroxide safe in cosmetics?

Corrosive (Cat. 1B, H314); causes severe skin burns and eye damage; dermal LD50 200โ€“3000 mg/kg bw in rabbits with total skin destruction at high dose; must never exceed regulatory pH/concentration limits; professional-use-only designation required above 2%; acute lithium systemic toxicity possible via damaged skin The EU classifies Lithium Hydroxide as "restricted". Safety rating: POOR.

Is Lithium Hydroxide allowed in the EU?

Lithium Hydroxide EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lithium Hydroxide do in cosmetics?

Lithium Hydroxide functions as: Buffering / pH adjuster / hair straightening / depilatory agent. It is classified as a cosmetic ingredient in our database. CAS number: 1310-65-2 [^1_5].

What is the Margin of Safety for Lithium Hydroxide?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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