Lupinus Albus Protein

INCI: LUPINUS ALBUS PROTEIN

CAS Number
Not assigned (complex protein mixture)
Function
Skin conditioning, hair conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR reviewed (2022); deemed safe as used. No VCRP registrations at time of review.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Key concern: legume allergen cross-reactivity. CIR 2022 review documented positive skin prick tests and elevated IgE in patients cross-sensitized between lupin and peanut. Vicilin in lupin definitively inhibited IgE binding to peanut Ara h 1. EU food allergen (lupin is Annex II allergen under 1169/2011). Hydrolyzed forms may reduce but not eliminate risk. Products should carry allergen advisory. Not suitable for compromised-barrier applications without additional testing.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Lupinus Albus Protein safe in cosmetics?

Key concern: legume allergen cross-reactivity. CIR 2022 review documented positive skin prick tests and elevated IgE in patients cross-sensitized between lupin and peanut. Vicilin in lupin definitively inhibited IgE binding to peanut Ara h 1. EU food allergen (lupin is Annex II allergen under 1169/2011). Hydrolyzed forms may reduce but not eliminate risk. Products should carry allergen advisory. Not suitable for compromised-barrier applications without additional testing. The EU classifies Lupinus Albus Protein as "permitted". Safety rating: MODERATE.

Is Lupinus Albus Protein allowed in the EU?

Lupinus Albus Protein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lupinus Albus Protein do in cosmetics?

Lupinus Albus Protein functions as: Skin conditioning, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (complex protein mixture).

What is the Margin of Safety for Lupinus Albus Protein?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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