Is Lysozyme safe in cosmetics?
Lysozyme has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Lysozyme
INCI: LYSOZYME
Lysozyme (CAS 12650-88-3 / 9001-63-2) is a cosmetic cosmetic ingredient functioning as Antimicrobial enzyme, skin conditioning agent; muramidase that hydrolyzes. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 12650-88-3 / 9001-63-2 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial enzyme, skin conditioning agent; muramidase that hydrolyzes bacterial cell walls
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — GRAS for food use (21 CFR 184.1550); not restricted for cosmetic use. No specific CIR monograph.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Lysozyme.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
4 property records from structured ingredient metadata.
acne
{"cas_number": "9001-63-2", "anti_acne_mechanism": "antibacterial", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "p_acnes_mic_ug_per_ml": "100-500", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne":…
anti_aging
{"anti_aging_claim": "anti-inflammatory, antimicrobial", "mechanism_of_action": "Enzymatic activity, targeted protein modification", "target_skin_layer": "epidermis, dermis", "collagen_stimulation": "Moderate", "elastin_protection": "Moderate", "wrinkle_reduction_pct": "5-10", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "No", "placebo_controlled": "Yes", "published_j…
deodorant
{"cas_number": "9001-63-2", "ingredient_class": "antimicrobial_deodorant", "mechanism_of_action": "bacterial_growth_inhibition", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "8-12", "odor_reduction_pct": "40-60", "bacteriostatic": "yes", "bactericidal": "yes", "target_bacteria": "broad_spectrum", "microbiome_impact": "selective", "axillary_microbiome_effect": "va…
preservative
{"preservative_class": "Enzyme", "antimicrobial_spectrum_bacteria_gp": "Excellent", "antimicrobial_spectrum_bacteria_gn": "Weak", "antimicrobial_spectrum_yeast": "Weak", "antimicrobial_spectrum_mold": "Weak", "mic_staph_aureus_ppm": "50", "mic_e_coli_ppm": "2000", "mic_pseudomonas_ppm": "2500", "mic_candida_albicans_ppm": "1500", "mic_aspergillus_niger_ppm": "2000", "challenge_test_pass_concentrat…
Expert Verdict
Expert safety assessment and concern-level summary for Lysozyme.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is Lysozyme allowed in the EU?
Lysozyme EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lysozyme do in cosmetics?
Lysozyme functions as: Antimicrobial enzyme, skin conditioning agent; muramidase that hydrolyzes bacterial cell walls. It is classified as a cosmetic ingredient in our database. CAS number: 12650-88-3 / 9001-63-2.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Antioxidant
Denatured Lysozyme
Moderate
Chemical family
Antimicrobial
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Skin conditioning
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