Lysozyme

INCI: LYSOZYME

CAS Number
12650-88-3 / 9001-63-2
Function
Antimicrobial enzyme, skin conditioning agent; muramidase that hydrolyzes bacterial cell walls
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” GRAS for food use (21 CFR 184.1550); not restricted for cosmetic use. No specific CIR monograph.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Egg allergen. Label per EU Reg. 1223/2009 Article 19 if egg-derived. Inhalation risk in powder-handling (occupational asthma documented). Ensure microbial purity of enzyme source.

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Lysozyme safe in cosmetics?

Egg allergen. Label per EU Reg. 1223/2009 Article 19 if egg-derived. Inhalation risk in powder-handling (occupational asthma documented). Ensure microbial purity of enzyme source. The EU classifies Lysozyme as "permitted". Safety rating: GOOD.

Is Lysozyme allowed in the EU?

Lysozyme EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lysozyme do in cosmetics?

Lysozyme functions as: Antimicrobial enzyme, skin conditioning agent; muramidase that hydrolyzes bacterial cell walls. It is classified as a cosmetic ingredient in our database. CAS number: 12650-88-3 / 9001-63-2.

What is the Margin of Safety for Lysozyme?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Lysozyme in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Lysozyme in your formulation.