Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Magnesium Fluoride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | ca.175 ppm | oral | rat | oral | REACH |
| LOAEL | ca.2.5 other | oral | mouse | oral | REACH |
Expert Verdict
Fluoride toxicity risk if ingested in excessive amounts (particularly in children). Chronic overexposure can cause dental or skeletal fluorosis.. Inhibits enamel demineralization while supporting remineralization; lower solubility compared to sodium fluoride, which affects bioavailability.
Regulatory Flags
Frequently Asked Questions
Is Magnesium Fluoride safe in cosmetics?
Fluoride toxicity risk if ingested in excessive amounts (particularly in children). Chronic overexposure can cause dental or skeletal fluorosis.. Inhibits enamel demineralization while supporting remineralization; lower solubility compared to sodium fluoride, which affects bioavailability. The EU classifies Magnesium Fluoride as "restricted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is Magnesium Fluoride allowed in the EU?
Magnesium Fluoride EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Magnesium Fluoride do in cosmetics?
Magnesium Fluoride functions as: Antiplaque, oral care. It is classified as a cosmetic ingredient in our database. CAS number: 7783-40-6.
What is the Margin of Safety for Magnesium Fluoride?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Magnesium Fluoride?
The NOAEL (No Observed Adverse Effect Level) for Magnesium Fluoride is ca.175 ppm based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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