Manganese Gluconate

INCI: MANGANESE GLUCONATE

CAS Number
6485-39-8
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed in cosmetics; also GRAS as a food-grade nutrient (USP/FCC standard)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally well tolerated; one of the best-characterized manganese salts due to food/pharma use; mild sensitization possible at high concentrations. Light pink powder; soluble in hot water; slightly hygroscopic; supports collagen production and skin elasticity; commercial grades carry โ‰ค20 ppm heavy metals and Mn content of ~11.2-11.6% (dehydrate basis)

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Concern Level: Moderate

Regulatory Flags

potential-allergen fda_food_additive

Frequently Asked Questions

Is Manganese Gluconate safe in cosmetics?

Generally well tolerated; one of the best-characterized manganese salts due to food/pharma use; mild sensitization possible at high concentrations. Light pink powder; soluble in hot water; slightly hygroscopic; supports collagen production and skin elasticity; commercial grades carry โ‰ค20 ppm heavy metals and Mn content of ~11.2-11.6% (dehydrate basis) The EU classifies Manganese Gluconate as "permitted". Safety rating: MODERATE.

Is Manganese Gluconate allowed in the EU?

Manganese Gluconate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Manganese Gluconate do in cosmetics?

Manganese Gluconate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 6485-39-8.

What is the Margin of Safety for Manganese Gluconate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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