Moderate Cosmetic Ingredient NOAEL Data

Matricaria Recutita Flower Oil

INCI: MATRICARIA RECUTITA FLOWER OIL (UPDATED SYNONYM: CHAMOMILLA RECUTITA FLOWER OIL)

Matricaria Recutita Flower Oil (CAS 84082-60-0) is a cosmetic cosmetic ingredient functioning as Masking, perfuming, skin conditioning, soothing. Reported NOAEL =200 mg/kg/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 84082-60-0 →

Auto-generated CPSR Part A draft with source citations
Function
Masking, perfuming, skin conditioning, soothing
Safety Rating
MODERATE

Chemistry & Identifiers

EC Number
282-006-5

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes Allowed; chamomile oil is generally recognized as safe (GRAS) for flavoring

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Matricaria Recutita Flower Oil.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for Matricaria Recutita Flower Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =200 mg/kg/d oral rat oral toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat oral toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat oral toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat oral toxicity CIR_vision_codex

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Biocide
Regulatory List Membership (2)
EU Regulated in Personal Care EU Restricted for Children (Cosmetics)

Expert Verdict

Expert safety assessment and concern-level summary for Matricaria Recutita Flower Oil.

Regulatory Flags

plant-oil potential-allergen fragrance-component eu_children_restricted

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Matricaria Recutita Flower Oil by CAS number or substance name.

Studies
4
Lowest NOAEL
200 mg/kg/d
Highest NOAEL
200 mg/kg/d
CIR_vision_codex

Chemical Function

Deodorizer Softener and conditioner Fragrance

Regulatory Lists

children; Europe; Personal care children; Europe; Personal care - hair styling and care - shampoo children; Europe; Personal care - specialized bath products - bubble bath children; Europe; Personal care - dental care - toothpaste Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
58
View full pharmaceutical profile →

Frequently Asked Questions

Is Matricaria Recutita Flower Oil safe in cosmetics?

Matricaria Recutita Flower Oil has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 4 toxicological study endpoint(s) are available in our database.

Is Matricaria Recutita Flower Oil allowed in the EU?

Matricaria Recutita Flower Oil EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Matricaria Recutita Flower Oil do in cosmetics?

Matricaria Recutita Flower Oil functions as: Masking, perfuming, skin conditioning, soothing. It is classified as a cosmetic ingredient in our database. CAS number: 84082-60-0.

What is the NOAEL for Matricaria Recutita Flower Oil?

The NOAEL (No Observed Adverse Effect Level) for Matricaria Recutita Flower Oil is =200 mg/kg/d based on a oral toxicity study via oral route in rat. A total of 4 study endpoints are available. Source: CIR_vision_codex.

Is Matricaria Recutita Flower Oil used outside cosmetics?

Matricaria Recutita Flower Oil also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Matricaria Recutita Flower Oil have different safety status in cosmetics vs industrial chemicals?

Matricaria Recutita Flower Oil is classified GHS Danger (H304, H315, H317, H412) in the chemicals database but is restricted in EU cosmetics.

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