Melia Azadirachta Leaf Extract

INCI: MELIA AZADIRACHTA LEAF EXTRACT

CAS Number
84696-25-3 / 90063-92-6
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contact dermatitis possible in sensitized individuals; contains azadirachtin and other limonoids - safe at typical cosmetic concentrations for topical use. The most widely used neem-derived cosmetic ingredient; well-documented antimicrobial, anti-inflammatory, and antioxidant properties; supplied by major cosmetic ingredient houses (Croda, Provital, Vantage)

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Melia Azadirachta Leaf Extract safe in cosmetics?

Contact dermatitis possible in sensitized individuals; contains azadirachtin and other limonoids - safe at typical cosmetic concentrations for topical use. The most widely used neem-derived cosmetic ingredient; well-documented antimicrobial, anti-inflammatory, and antioxidant properties; supplied by major cosmetic ingredient houses (Croda, Provital, Vantage) The EU classifies Melia Azadirachta Leaf Extract as "permitted". Safety rating: MODERATE.

Is Melia Azadirachta Leaf Extract allowed in the EU?

Melia Azadirachta Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Melia Azadirachta Leaf Extract do in cosmetics?

Melia Azadirachta Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-25-3 / 90063-92-6.

What is the Margin of Safety for Melia Azadirachta Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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