Melia Azadirachta Seed Extract

INCI: MELIA AZADIRACHTA SEED EXTRACT

CAS Number
84696-25-3
Function
Skin conditioning, emollient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Seed-derived neem products contain higher concentrations of azadirachtin and other triterpenoids than leaf extracts - higher sensitization potential; must not be confused with neem seed oil (different INCI); oral toxicity is significant. Concentrated source of azadirachtin and nimbin; the seed extract is more bioactive than leaf or flower extracts, making it effective but requiring more careful formulation and dose control

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Melia Azadirachta Seed Extract safe in cosmetics?

Seed-derived neem products contain higher concentrations of azadirachtin and other triterpenoids than leaf extracts - higher sensitization potential; must not be confused with neem seed oil (different INCI); oral toxicity is significant. Concentrated source of azadirachtin and nimbin; the seed extract is more bioactive than leaf or flower extracts, making it effective but requiring more careful formulation and dose control The EU classifies Melia Azadirachta Seed Extract as "permitted". Safety rating: MODERATE.

Is Melia Azadirachta Seed Extract allowed in the EU?

Melia Azadirachta Seed Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Melia Azadirachta Seed Extract do in cosmetics?

Melia Azadirachta Seed Extract functions as: Skin conditioning, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 84696-25-3.

What is the Margin of Safety for Melia Azadirachta Seed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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