Is Melissa Officinalis Leaf Extract safe in cosmetics?
Melissa Officinalis Leaf Extract has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Melissa Officinalis Leaf Extract
INCI: MELISSA OFFICINALIS LEAF EXTRACT
Melissa Officinalis Leaf Extract (CAS 84082-61-1) is a cosmetic cosmetic ingredient functioning as Skin conditioning, tonic, soothing. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 84082-61-1 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, tonic, soothing
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - Melissa officinalis leaf extract is GRAS for food; no FDA cosmetic prohibition
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Melissa Officinalis Leaf Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
3 property records from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "antioxidant-protection, anti-inflammatory", "mechanism_of_action": "Bioactive phytochemicals, antioxidant compounds", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "5-10", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Phy…
anti_pollution
{"cas_number": "84082-61-1", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulati…
depigmentation
{"cas_number": "84082-61-1", "ingredient_class": "combined_mechanism", "primary_mechanism_of_action": "Traditional Asian/Ayurvedic brightening ingredient", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduction_pct_clinical": "15-30", "onse…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Flavouring and nutrient
Fragrance
Humectant
Softener and conditioner
Regulatory List Membership (5)
EU Regulated in Personal Care
EU Restricted for Children (Cosmetics)
EU Restricted for Children (Cosmetics)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Melissa Officinalis Leaf Extract.
Regulatory Flags
plant-extract
potential-allergen
eu_children_restricted
ifra_fragrance
fda_food_additive
Chemical Function
Deodorizer
Humectant
Softener and conditioner
Fragrance
Regulatory Lists
Europe; Personal care
Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Melissa Officinalis Leaf Extract allowed in the EU?
Melissa Officinalis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Melissa Officinalis Leaf Extract do in cosmetics?
Melissa Officinalis Leaf Extract functions as: Skin conditioning, tonic, soothing. It is classified as a cosmetic ingredient in our database. CAS number: 84082-61-1.
Compliance Tools
Check Melissa Officinalis Leaf Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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