Moderate Cosmetic Ingredient NOAEL Data

Mentha Spicata Flower/Leaf/Stem Oil

INCI: MENTHA SPICATA FLOWER/LEAF/STEM OIL

CAS Number
84696-51-5
Function
Fragrance, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. Spearmint oil is GRAS for food use; no cosmetic-specific prohibitions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Mentha Spicata Flower/Leaf/Stem Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 93 mg/kg bw/day oral rat oral REACH
NOAEL 93 mg/kg bw/day oral - oral REACH
LOAEL 30 mg/kg bw/day oral rat oral REACH
LOAEL 30 mg/kg bw/day oral - oral REACH
NOAEL 93 mg/kg bw/day oral rat oral REACH
NOAEL 93 mg/kg bw/day oral - oral REACH
LOAEL 30 mg/kg bw/day oral rat oral REACH
LOAEL 30 mg/kg bw/day oral - oral REACH
LOAEL 750 mg/kg bw/day oral mouse oral REACH
LOAEL 750 mg/kg bw/day oral - oral REACH

Expert Verdict

Essential oil - can cause contact sensitization or irritation. Contains limonene (a declared allergen under EU rules). Use at appropriate dilution levels. Essential oil distilled from flowers, leaves, and stems of spearmint. Dual-function ingredient: provides fragrance while also conditioning and maintaining skin in good condition. Carvone-rich profile

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Concern Level: Moderate

Regulatory Flags

plant-oil essential-oil potential-allergen fragrance-component fda_food_additive

Frequently Asked Questions

Is Mentha Spicata Flower/Leaf/Stem Oil safe in cosmetics?

Essential oil - can cause contact sensitization or irritation. Contains limonene (a declared allergen under EU rules). Use at appropriate dilution levels. Essential oil distilled from flowers, leaves, and stems of spearmint. Dual-function ingredient: provides fragrance while also conditioning and maintaining skin in good condition. Carvone-rich profile The EU classifies Mentha Spicata Flower/Leaf/Stem Oil as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.

Is Mentha Spicata Flower/Leaf/Stem Oil allowed in the EU?

Mentha Spicata Flower/Leaf/Stem Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Mentha Spicata Flower/Leaf/Stem Oil do in cosmetics?

Mentha Spicata Flower/Leaf/Stem Oil functions as: Fragrance, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-51-5.

What is the Margin of Safety for Mentha Spicata Flower/Leaf/Stem Oil?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Mentha Spicata Flower/Leaf/Stem Oil?

The NOAEL (No Observed Adverse Effect Level) for Mentha Spicata Flower/Leaf/Stem Oil is 93 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.

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