Mentha Spicata Leaf Extract
INCI: MENTHA SPICATA LEAF EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Mentha Spicata Leaf Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 93 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 93 mg/kg bw/day | oral | - | oral | REACH |
| LOAEL | 30 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 30 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 93 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 93 mg/kg bw/day | oral | - | oral | REACH |
| LOAEL | 30 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 30 mg/kg bw/day | oral | - | oral | REACH |
| LOAEL | 750 mg/kg bw/day | oral | mouse | oral | REACH |
| LOAEL | 750 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Generally well tolerated. Potential for sensitization at high concentrations due to constituent essential oil compounds. Solvent extract specifically from the leaves of spearmint. Unlike the herb extract (which is classified as fragrance), this leaf extract is classified as a skin conditioning agent - indicating it is typically used for functional skincare benefits rather than solely for scent
Regulatory Flags
Frequently Asked Questions
Is Mentha Spicata Leaf Extract safe in cosmetics?
Generally well tolerated. Potential for sensitization at high concentrations due to constituent essential oil compounds. Solvent extract specifically from the leaves of spearmint. Unlike the herb extract (which is classified as fragrance), this leaf extract is classified as a skin conditioning agent - indicating it is typically used for functional skincare benefits rather than solely for scent The EU classifies Mentha Spicata Leaf Extract as "prohibited". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Mentha Spicata Leaf Extract allowed in the EU?
Mentha Spicata Leaf Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Mentha Spicata Leaf Extract do in cosmetics?
Mentha Spicata Leaf Extract functions as: Skin Conditioning - maintains the skin in good condition. It is classified as a cosmetic ingredient in our database. CAS number: 84696-51-5.
What is the Margin of Safety for Mentha Spicata Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Mentha Spicata Leaf Extract?
The NOAEL (No Observed Adverse Effect Level) for Mentha Spicata Leaf Extract is 93 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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