Menthyl Ethylamido Oxalate

INCI: MENTHYL ETHYLAMIDO OXALATE

CAS Number
85721-05-7 (commonly referenced)
Function
Cooling agent, Skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not on any prohibited/restricted list; falls under general safety provisions for cosmetic ingredients

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low toxicity profile in published evaluations; potential for mild skin irritation at high concentrations; patch testing recommended for sensitive-skin formulations. Synthetic cooling agent delivering a long-lasting, smooth cooling sensation without the strong minty odor of menthol; activates TRPM8 cold receptors; often used alongside WS-3 and menthyl lactate to build layered cooling effects

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Concern Level: High

Frequently Asked Questions

Is Menthyl Ethylamido Oxalate safe in cosmetics?

Low toxicity profile in published evaluations; potential for mild skin irritation at high concentrations; patch testing recommended for sensitive-skin formulations. Synthetic cooling agent delivering a long-lasting, smooth cooling sensation without the strong minty odor of menthol; activates TRPM8 cold receptors; often used alongside WS-3 and menthyl lactate to build layered cooling effects The EU classifies Menthyl Ethylamido Oxalate as "permitted". Safety rating: MODERATE.

Is Menthyl Ethylamido Oxalate allowed in the EU?

Menthyl Ethylamido Oxalate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Menthyl Ethylamido Oxalate do in cosmetics?

Menthyl Ethylamido Oxalate functions as: Cooling agent, Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 85721-05-7 (commonly referenced).

What is the Margin of Safety for Menthyl Ethylamido Oxalate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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