Menthyl PCA

INCI: MENTHYL PCA

CAS Number
64519-44-4 / 68127-22-0
Function
Humectant, Skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted; falls under general cosmetic safety provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Rated as safe; generally well-tolerated; plant and synthetic origins available. Dual-function ingredient combining the cooling effect of menthol with the moisturizing properties of PCA (pyrrolidone carboxylic acid), a natural moisturizing factor (NMF) component; provides immediate and long-lasting cooling; broad compatibility with other cosmetic ingredients

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Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Menthyl PCA safe in cosmetics?

Rated as safe; generally well-tolerated; plant and synthetic origins available. Dual-function ingredient combining the cooling effect of menthol with the moisturizing properties of PCA (pyrrolidone carboxylic acid), a natural moisturizing factor (NMF) component; provides immediate and long-lasting cooling; broad compatibility with other cosmetic ingredients The EU classifies Menthyl PCA as "permitted". Safety rating: MODERATE.

Is Menthyl PCA allowed in the EU?

Menthyl PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Menthyl PCA do in cosmetics?

Menthyl PCA functions as: Humectant, Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 64519-44-4 / 68127-22-0.

What is the Margin of Safety for Menthyl PCA?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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