Is Isomalt safe in cosmetics?
Isomalt has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Isomalt
Also known as: D-arabino-Hexitol, 6-O-alpha-D-glucopyranosyl-, (2xi)-, C-Isomaltidex, Isomalt DC 110, Palatinitol, Palatinose PNP (+15 more)
INCI: ISOMALT
Isomalt (CAS 64519-82-0) is a cosmetic cosmetic ingredient functioning as Humectant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 64519-82-0 →
Auto-generated CPSR Part A draft with source citations
Function
Humectant
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(3R,4R,5R)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,4,5-pentol
InChIKey
SERLAGPUMNYUCK-BLEZHGCXSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FDA GRAS for food use; no cosmetic restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isomalt.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
humectant
{"cas_number": "64519-82-0", "ingredient_class": "humectant/polyol/sugar_derivative", "molecular_weight_Da": "344.31", "chemical_type": "polyol", "water_binding_mechanism": "hydrogen_bonding/hygroscopic", "water_holding_capacity_g_per_g": "0.4-0.6", "hygroscopicity_at_50_RH": "moderate", "hygroscopicity_at_80_RH": "good", "NMF_component": "no", "NMF_percentage_natural": "0", "TEWL_reduction_pct": …
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Evaluation
HYDROGENATED ISOMALTULOSE | 1985 | NOT SPECIFIED | TRS 733-JECFA 29/34 | FAS 20-JECFA 29/207
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-caking agent
Filler
Flavouring and nutrient
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for Isomalt.
Regulatory Flags
natural-origin
jecfa_safe
Known Synonyms
D-arabino-Hexitol, 6-O-alpha-D-glucopyranosyl-, (2xi)-
C-Isomaltidex
Isomalt DC 110
Palatinitol
Palatinose PNP
Hydrogenated isomaltulose
GalenIQ 801
IsoMaltidex 16502
GalenIQ 960
Isomalt PF
Isomaltidex
Palatinit
Palatinit C
Palatinit GS
Palatinit GSP
Palatinit M
Palatinit PM
Palatinit PN
Palatinit PNM 2
Palatinit PNP
Chemical Function
Humectant
Filler
Flavouring and nutrient
Anti-caking agent
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Isomalt
E Number
E953
ADI
NOT SPECIFIED mg/kg bw
Food Category
sweetener
Frequently Asked Questions
Is Isomalt allowed in the EU?
Isomalt EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isomalt do in cosmetics?
Isomalt functions as: Humectant. It is classified as a cosmetic ingredient in our database. CAS number: 64519-82-0.
Is Isomalt used outside cosmetics?
Isomalt also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isomalt compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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