Methacryloylethyl Phosphate
INCI: METHACRYLOYLETHYL PHOSPHATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Methacryloylethyl Phosphate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Phosphate ester with a reactive methacrylate double bond; handle with care as a monomer (skin/eye irritant in pure form). The phosphate group provides adhesion to the nail plate while the methacrylate group enables polymerization, making it valuable as an adhesion-promoting monomer in UV-cure nail systems
Frequently Asked Questions
Is Methacryloylethyl Phosphate safe in cosmetics?
Phosphate ester with a reactive methacrylate double bond; handle with care as a monomer (skin/eye irritant in pure form). The phosphate group provides adhesion to the nail plate while the methacrylate group enables polymerization, making it valuable as an adhesion-promoting monomer in UV-cure nail systems The EU classifies Methacryloylethyl Phosphate as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is Methacryloylethyl Phosphate allowed in the EU?
Methacryloylethyl Phosphate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Methacryloylethyl Phosphate do in cosmetics?
Methacryloylethyl Phosphate functions as: Nail conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 52628-03-2.
What is the Margin of Safety for Methacryloylethyl Phosphate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Methacryloylethyl Phosphate?
The NOAEL (No Observed Adverse Effect Level) for Methacryloylethyl Phosphate is 100 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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