Methyl Butyrate

INCI: METHYL BUTYRATE

CAS Number
623-42-7
Function
Fragrance / masking agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Allowed - GRAS (Generally Recognized as Safe) for food use; no cosmetic prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low concern at typical fragrance concentrations; volatile ester - inhalation irritation possible at high concentrations; flammable. Molecular formula C₅H₁₀O₂; fruity, apple/pineapple-like odor; low molecular weight volatile ester; also used extensively as a food flavoring agent

⚠️
Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Methyl Butyrate safe in cosmetics?

Low concern at typical fragrance concentrations; volatile ester - inhalation irritation possible at high concentrations; flammable. Molecular formula C₅H₁₀O₂; fruity, apple/pineapple-like odor; low molecular weight volatile ester; also used extensively as a food flavoring agent The EU classifies Methyl Butyrate as "prohibited". Safety rating: MODERATE.

Is Methyl Butyrate allowed in the EU?

Methyl Butyrate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Butyrate do in cosmetics?

Methyl Butyrate functions as: Fragrance / masking agent. It is classified as a cosmetic ingredient in our database. CAS number: 623-42-7.

What is the Margin of Safety for Methyl Butyrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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