Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Highly flammable (flash point 6°C / 43°F); classified GHS02/GHS05/GHS07 - causes serious eye damage (H318), harmful if inhaled (H332). LD₅₀ oral (rabbit) = 5,000 mg/kg. Must be handled with appropriate safety precautions in manufacturing.. Colourless liquid with a fresh, harsh, rum-like fruity odour (strawberry, apple notes); molecular formula C₄H₈O₂ (MW 88.11); boiling point 79°C; water solubility ~5 g/100 mL at 20°C; also used industrially as a solvent for cellulose nitrate and lacquers
Regulatory Flags
Frequently Asked Questions
Is Methyl Propionate safe in cosmetics?
Highly flammable (flash point 6°C / 43°F); classified GHS02/GHS05/GHS07 - causes serious eye damage (H318), harmful if inhaled (H332). LD₅₀ oral (rabbit) = 5,000 mg/kg. Must be handled with appropriate safety precautions in manufacturing.. Colourless liquid with a fresh, harsh, rum-like fruity odour (strawberry, apple notes); molecular formula C₄H₈O₂ (MW 88.11); boiling point 79°C; water solubility ~5 g/100 mL at 20°C; also used industrially as a solvent for cellulose nitrate and lacquers The EU classifies Methyl Propionate as "permitted". Safety rating: MODERATE.
Is Methyl Propionate allowed in the EU?
Methyl Propionate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Propionate do in cosmetics?
Methyl Propionate functions as: Perfuming (fragrance). It is classified as a cosmetic ingredient in our database. CAS number: 554-12-1.
What is the Margin of Safety for Methyl Propionate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Methyl Propionate compliance across multiple jurisdictions:
Related Ingredients
Is Methyl Propionate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methyl Propionate in your formulation.