Is Methylenedioxybenzoyl Ethyl PABA safe in cosmetics?
Methylenedioxybenzoyl Ethyl PABA has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methylenedioxybenzoyl Ethyl PABA
Also known as: UNII-5U05P81M8W, Benzoic acid, 4-((1,3-benzodioxol-5-ylcarbonyl)amino)-, ethyl ester, Foretin AP-1
INCI: METHYLENEDIOXYBENZOYL ETHYL PABA
Methylenedioxybenzoyl Ethyl PABA (CAS 333432-71-6) is a cosmetic cosmetic ingredient functioning as UV absorber / UV filter. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 333432-71-6 →
Auto-generated CPSR Part A draft with source citations
Function
UV absorber / UV filter
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
ethyl 4-(1,3-benzodioxole-5-carbonylamino)benzoate
InChIKey
MNAPLMLDXHLQRT-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not listed among the 16 FDA-approved OTC sunscreen active ingredients in the US; would require an NDA/new monograph pathway for use as an active UV filter
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methylenedioxybenzoyl Ethyl PABA.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for Methylenedioxybenzoyl Ethyl PABA.
Known Synonyms
UNII-5U05P81M8W
Benzoic acid, 4-((1,3-benzodioxol-5-ylcarbonyl)amino)-, ethyl ester
Foretin AP-1
Chemical Function
Humectant
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1504889
Frequently Asked Questions
Is Methylenedioxybenzoyl Ethyl PABA allowed in the EU?
Methylenedioxybenzoyl Ethyl PABA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methylenedioxybenzoyl Ethyl PABA do in cosmetics?
Methylenedioxybenzoyl Ethyl PABA functions as: UV absorber / UV filter. It is classified as a cosmetic ingredient in our database. CAS number: 333432-71-6.
Is Methylenedioxybenzoyl Ethyl PABA used outside cosmetics?
Methylenedioxybenzoyl Ethyl PABA also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Methylenedioxybenzoyl Ethyl PABA compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Benzylidene Camphor Sulfonic Acid
Excellent
Same category
UV filter (broadband UVB + UVA absorb...
Dioctylaminoethoxytriazine Aminopropyl Silsesquioxane Silicate
Excellent
Same category
Film forming agent that creates prote...
Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (MBBT)
Excellent
Same category
UV filter, light stabilizer
Triethoxycaprylylsilane
Excellent
Same category
Binder, Surface Modifier, Skin Condit...
Trimethoxycaprylylsilane
Excellent
Same category
Surface modifier, binder, skin condit...
Tris-Biphenyl Triazine
Excellent
Same category
UV Filter – most efficient UVB + UVA2...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
METHACRYLIC ACID/PEG-6 METHACRYLATE/PEG-6 DIMETHACRYLATE CROSSPOLYMER.
Good
Browse nearby
Film Forming
METHIONYL R-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 HEXAPEPTIDE-40
Good
Browse nearby
Skin Protecting
METHIONYL R-SALMON OLIGOPEPTIDE-1 SH-OLIGOPEPTIDE-2
Good
Browse nearby
Antioxidant, Skin Protecting
Is Methylenedioxybenzoyl Ethyl PABA in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methylenedioxybenzoyl Ethyl PABA in your formulation.