Methylfurfural

INCI: METHYLFURFURAL

CAS Number
620-02-0
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition; FEMA GRAS 2702 for flavoring; permitted in cosmetics as a fragrance component

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

RIFM safety assessment concludes it is safe at current declared use levels; not expected to be genotoxic (read-across from furfural CAS 98-01-1); MOE > 100 for repeated dose and reproductive toxicity endpoints; photoallergy not fully evaluated due to lack of validated in vitro data. Clear, colorless to yellow-brown liquid; caramellic, spicy, sweet, warm odor profile; medium odor strength; substantivity > 1 hour at 100%; readily biodegradable

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Concern Level: High

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Methylfurfural safe in cosmetics?

RIFM safety assessment concludes it is safe at current declared use levels; not expected to be genotoxic (read-across from furfural CAS 98-01-1); MOE > 100 for repeated dose and reproductive toxicity endpoints; photoallergy not fully evaluated due to lack of validated in vitro data. Clear, colorless to yellow-brown liquid; caramellic, spicy, sweet, warm odor profile; medium odor strength; substantivity > 1 hour at 100%; readily biodegradable The EU classifies Methylfurfural as "permitted". Safety rating: MODERATE.

Is Methylfurfural allowed in the EU?

Methylfurfural EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylfurfural do in cosmetics?

Methylfurfural functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 620-02-0.

What is the Margin of Safety for Methylfurfural?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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