Mulberry Extract

INCI: MORUS ALBA ROOT EXTRACT

CAS Number
90064-11-2
Function
Skin brightening / Antioxidant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permits use as a cosmetic ingredient without pre-market approval. Not classified as a sunscreen active under OTC Drug Monograph. No CIR safety assessment published specifically for Morus alba root extract. Subject to MoCRA (2022) requirements. Any therapeutic claims would require drug approval pathway.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU: permitted without concentration restrictions under Regulation (EC) 1223/2009; not listed in Annex II (prohibited) or Annex III (restricted); not captured by 2024/996 restrictions applied to kojic acid and arbutin; no SCCS opinion. US: FDA permits cosmetic use without pre-market approval; not a sunscreen monograph active; subject to MoCRA. Efficacy: 29% improvement in MASI score vs 2% placebo at 75% extract concentration over 8 weeks. Primary function: tyrosinase inhibition via oxyresveratrol. Regulatory-compliant alternative to restricted arbutin and kojic acid.

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Concern Level: Low

Regulatory Flags

tyrosinase-inhibitor skin-lightening botanical-extract antioxidant hair-conditioning photodegradation-risk no-sccs-opinion mocra-subject limited-dermal-absorption-data no-phototoxicity-data

Frequently Asked Questions

Is Mulberry Extract safe in cosmetics?

EU: permitted without concentration restrictions under Regulation (EC) 1223/2009; not listed in Annex II (prohibited) or Annex III (restricted); not captured by 2024/996 restrictions applied to kojic acid and arbutin; no SCCS opinion. US: FDA permits cosmetic use without pre-market approval; not a sunscreen monograph active; subject to MoCRA. Efficacy: 29% improvement in MASI score vs 2% placebo at 75% extract concentration over 8 weeks. Primary function: tyrosinase inhibition via oxyresveratrol. Regulatory-compliant alternative to restricted arbutin and kojic acid. The EU classifies Mulberry Extract as "permitted". Safety rating: GOOD.

Is Mulberry Extract allowed in the EU?

Mulberry Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Mulberry Extract do in cosmetics?

Mulberry Extract functions as: Skin brightening / Antioxidant. It is classified as a Active Ingredient in our database. CAS number: 90064-11-2.

What is the Margin of Safety for Mulberry Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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