Regulatory Status
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Safety Data
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Expert Verdict
Patent-stage ingredient with fewer structural alerts than dopamine analogs (no catechol group). Requires complete toxicological dataset including acute toxicity, repeated-dose studies, genotoxicity assessment, and sensitization testing for cosmetic product safety review.
Regulatory Flags
Frequently Asked Questions
Is N-Nicotinoyl Tyramine safe in cosmetics?
Patent-stage ingredient with fewer structural alerts than dopamine analogs (no catechol group). Requires complete toxicological dataset including acute toxicity, repeated-dose studies, genotoxicity assessment, and sensitization testing for cosmetic product safety review. The EU classifies N-Nicotinoyl Tyramine as "permitted". Safety rating: MODERATE.
Is N-Nicotinoyl Tyramine allowed in the EU?
N-Nicotinoyl Tyramine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does N-Nicotinoyl Tyramine do in cosmetics?
N-Nicotinoyl Tyramine functions as: Skin conditioning — tyrosinase inhibitor / melanogenesis suppressor (via MITF gene downregulation). It is classified as a cosmetic ingredient in our database. CAS number: Not widely assigned.
What is the Margin of Safety for N-Nicotinoyl Tyramine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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