Good Cosmetic Ingredient NOAEL Data

P,ALPHA-DIMETHYLSTYRENE

CAS Number
1195-32-0
Function
Perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

2 study endpoints found for P,ALPHA-DIMETHYLSTYRENE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 0.6 mg/kg bw/day oral rat Subchronic COSMOS_DB
dose_tested 0.6 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

P,ALPHA-DIMETHYLSTYRENE is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted fragrance needs-enrichment ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is P,ALPHA-DIMETHYLSTYRENE safe in cosmetics?

P,ALPHA-DIMETHYLSTYRENE is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions. The EU classifies P,ALPHA-DIMETHYLSTYRENE as "Permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is P,ALPHA-DIMETHYLSTYRENE allowed in the EU?

P,ALPHA-DIMETHYLSTYRENE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does P,ALPHA-DIMETHYLSTYRENE do in cosmetics?

P,ALPHA-DIMETHYLSTYRENE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 1195-32-0.

What is the NOAEL for P,ALPHA-DIMETHYLSTYRENE?

The NOAEL (No Observed Adverse Effect Level) for P,ALPHA-DIMETHYLSTYRENE is 0.6 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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