Good Cosmetic Ingredient NOAEL Data

PEG-10 PROPYLENE GLYCOL

CAS Number
9003-11-6
Function
Humectant, Solvent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status Permitted
🇺🇸 US Status permitted
US Notes CIR: S - IJT 19(S2):43-89, 2000

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

10 study endpoints found for PEG-10 PROPYLENE GLYCOL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 25000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 30000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 480 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 3000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 200 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 500 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1000 mg/kg bw/day oral dog Subchronic COSMOS_DB
NOAEL 40 mg/kg bw/day oral dog Subchronic COSMOS_DB

Expert Verdict

PEG-10 PROPYLENE GLYCOL is listed in the EU CosIng database with functions: Humectant, Solvent It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted humectant needs-enrichment epa_safer_alternative fda_food_additive

Frequently Asked Questions

Is PEG-10 PROPYLENE GLYCOL safe in cosmetics?

PEG-10 PROPYLENE GLYCOL is listed in the EU CosIng database with functions: Humectant, Solvent It is permitted in the EU without specific restrictions. The EU classifies PEG-10 PROPYLENE GLYCOL as "Permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is PEG-10 PROPYLENE GLYCOL allowed in the EU?

PEG-10 PROPYLENE GLYCOL EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG-10 PROPYLENE GLYCOL do in cosmetics?

PEG-10 PROPYLENE GLYCOL functions as: Humectant, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6.

What is the NOAEL for PEG-10 PROPYLENE GLYCOL?

The NOAEL (No Observed Adverse Effect Level) for PEG-10 PROPYLENE GLYCOL is 25000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

Compliance Tools

Check PEG-10 PROPYLENE GLYCOL compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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