Excellent Cosmetic Ingredient NOAEL Data

Decylene/Butylene Glycol

Also known as: Decylene glycol

INCI: DECYLENE GLYCOL (AND) BUTYLENE GLYCOL

Decylene/Butylene Glycol (CAS 1119-86-4) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Humectant, Solvent, Preservative Booster. NOAEL 100 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 1119-86-4 →

Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Humectant, Solvent, Preservative Booster
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
C10H22O2
MW
174.28 g/mol
EC Number
214-288-2
PubChem CID
79141
IUPAC Name
decane-1,2-diol
InChIKey
YSRSBDQINUMTIF-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR assessed as safe; typical use levels 0.1-2%

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Decylene/Butylene Glycol.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Decylene/Butylene Glycol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =100 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID
NOAEL =1000 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Decylene/Butylene Glycol across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Fragrance Softener and conditioner
Regulatory List Membership (1)
IFRA Fragrance Transparency List

Expert Verdict

Expert safety assessment and concern-level summary for Decylene/Butylene Glycol.

Regulatory Flags

humectant penetration-enhancer preservative-booster cir-approved low-hazard ifra_fragrance

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Decylene/Butylene Glycol by CAS number or substance name.

Studies
2
Lowest NOAEL
100 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Decylene glycol

Chemical Function

Softener and conditioner Fragrance

Regulatory Lists

IFRA Transparency

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Decylene/Butylene Glycol safe in cosmetics?

Decylene/Butylene Glycol has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.

Is Decylene/Butylene Glycol allowed in the EU?

Decylene/Butylene Glycol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decylene/Butylene Glycol do in cosmetics?

Decylene/Butylene Glycol functions as: Skin Conditioning, Humectant, Solvent, Preservative Booster. It is classified as a cosmetic ingredient in our database. CAS number: 1119-86-4.

What is the NOAEL for Decylene/Butylene Glycol?

The NOAEL (No Observed Adverse Effect Level) for Decylene/Butylene Glycol is =100 mg/kg bw/day based on a short-term study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.

Is Decylene/Butylene Glycol used outside cosmetics?

Decylene/Butylene Glycol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Decylene/Butylene Glycol have different safety status in cosmetics vs industrial chemicals?

Decylene/Butylene Glycol is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.

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