Excellent Cosmetic Ingredient NOAEL Data

Decylene/Butylene Glycol

INCI: DECYLENE GLYCOL (AND) BUTYLENE GLYCOL

CAS Number
1119-86-4
Function
Skin Conditioning, Humectant, Solvent, Preservative Booster
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR assessed as safe; typical use levels 0.1-2%

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Decylene/Butylene Glycol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 100 mg/kg bw/day oral rat oral REACH

Expert Verdict

Blend of decylene glycol and butylene glycol providing skin conditioning, humectancy, and preservation boosting with strong CIR safety record and low hazard profile.

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Concern Level: None

Regulatory Flags

humectant penetration-enhancer preservative-booster cir-approved low-hazard ifra_fragrance

Frequently Asked Questions

Is Decylene/Butylene Glycol safe in cosmetics?

Blend of decylene glycol and butylene glycol providing skin conditioning, humectancy, and preservation boosting with strong CIR safety record and low hazard profile. The EU classifies Decylene/Butylene Glycol as "permitted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.

Is Decylene/Butylene Glycol allowed in the EU?

Decylene/Butylene Glycol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decylene/Butylene Glycol do in cosmetics?

Decylene/Butylene Glycol functions as: Skin Conditioning, Humectant, Solvent, Preservative Booster. It is classified as a cosmetic ingredient in our database. CAS number: 1119-86-4.

What is the Margin of Safety for Decylene/Butylene Glycol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Decylene/Butylene Glycol?

The NOAEL (No Observed Adverse Effect Level) for Decylene/Butylene Glycol is 100 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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