Perfluoroisohexane

INCI: PERFLUOROISOHEXANE

CAS Number
355-04-4 (perfluoro-2-methylpentane — verify via CosIng)
Function
Solvent, skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status restricted
US Notes Not specifically restricted by FDA; sister compound perfluorohexane assessed as low safety concern by FDA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PFAS with environmental persistence despite volatility; potential atmospheric transport as PFHxA precursor; inhalation exposure risk during application

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Concern Level: Moderate

Frequently Asked Questions

Is Perfluoroisohexane safe in cosmetics?

PFAS with environmental persistence despite volatility; potential atmospheric transport as PFHxA precursor; inhalation exposure risk during application The EU classifies Perfluoroisohexane as "prohibited". Safety rating: MODERATE.

Is Perfluoroisohexane allowed in the EU?

Perfluoroisohexane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Perfluoroisohexane do in cosmetics?

Perfluoroisohexane functions as: Solvent, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 355-04-4 (perfluoro-2-methylpentane — verify via CosIng).

What is the Margin of Safety for Perfluoroisohexane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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