Phenethyl Salicylate

INCI: PHENETHYL SALICYLATE

CAS Number
87-22-9
Function
Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics as fragrance ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Positive in BlueScreen genotoxicity assay at cytotoxic concentrations, but overall weight of evidence supports no genotoxic concern. Salicylate hydrolysis product โ€” avoid stacking with other salicylate sources in formulation. Not PBT.

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Concern Level: Low

Regulatory Flags

fragrance-component endocrine_disruptor ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Phenethyl Salicylate safe in cosmetics?

Positive in BlueScreen genotoxicity assay at cytotoxic concentrations, but overall weight of evidence supports no genotoxic concern. Salicylate hydrolysis product โ€” avoid stacking with other salicylate sources in formulation. Not PBT. The EU classifies Phenethyl Salicylate as "permitted". Safety rating: GOOD.

Is Phenethyl Salicylate allowed in the EU?

Phenethyl Salicylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phenethyl Salicylate do in cosmetics?

Phenethyl Salicylate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 87-22-9.

What is the Margin of Safety for Phenethyl Salicylate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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