Good Cosmetic Ingredient NOAEL Data

Phenoxyethyl Caprylate

Also known as: UNII-GMI5AN7T8U, 2-Phenoxyethyl octanoate, Ethanol, 2-phenoxy-, octanoate, Octanioic acid, 2-phenoxyethyl ester, Tegosoft XC

Phenoxyethyl Caprylate (CAS 23511-73-1) is classified as a cosmetic ingredient. Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 23511-73-1 →

Auto-generated CPSR Part A draft with source citations
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C16H24O3
MW
264.36 g/mol
EC Number
607-240-0
PubChem CID
59236950
IUPAC Name
2-phenoxyethyl octanoate
InChIKey
FTLLYZOWBWEERE-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not specifically restricted by FDA; general-use cosmetic ingredient

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Phenoxyethyl Caprylate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Phenoxyethyl Caprylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Expert Verdict

Expert safety assessment and concern-level summary for Phenoxyethyl Caprylate.

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Phenoxyethyl Caprylate by CAS number or substance name.

Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

UNII-GMI5AN7T8U 2-Phenoxyethyl octanoate Ethanol, 2-phenoxy-, octanoate Octanioic acid, 2-phenoxyethyl ester Tegosoft XC

Frequently Asked Questions

Is Phenoxyethyl Caprylate safe in cosmetics?

Phenoxyethyl Caprylate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Phenoxyethyl Caprylate allowed in the EU?

Phenoxyethyl Caprylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What is the NOAEL for Phenoxyethyl Caprylate?

The NOAEL (No Observed Adverse Effect Level) for Phenoxyethyl Caprylate is =1000 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Phenoxyethyl Caprylate used outside cosmetics?

Phenoxyethyl Caprylate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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