Phosphatidylserine

INCI: PHOSPHATIDYLSERINE

CAS Number
51446-62-9
Function
Skin conditioning agent
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR safe in present practices of use and concentration; FDA GRAS (food)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Anionic phospholipid with pH-sensitive behavior in aqueous formulations; potential soy allergen source depending on origin.

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Concern Level: Low

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Phosphatidylserine safe in cosmetics?

Anionic phospholipid with pH-sensitive behavior in aqueous formulations; potential soy allergen source depending on origin. The EU classifies Phosphatidylserine as "permitted". Safety rating: EXCELLENT.

Is Phosphatidylserine allowed in the EU?

Phosphatidylserine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phosphatidylserine do in cosmetics?

Phosphatidylserine functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 51446-62-9.

What is the Margin of Safety for Phosphatidylserine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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