Phytolacca Decandra Extract

INCI: PHYTOLACCA DECANDRA EXTRACT

CAS Number
85085-78-7 (reported)
Function
Pharmacologically active plant extract containing pokeweed mitogen, phytolaccosides, and pokeweed antiviral protein with cytotoxic and immunostimulatory properties
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA cosmetic ban; used in homeopathy but toxicity is well-documented

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU due to cytotoxic and immunostimulatory pokeweed mitogen and phytolaccoside content; permitted in US cosmetics with no specific FDA ban despite documented toxicity.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Phytolacca Decandra Extract safe in cosmetics?

Prohibited in EU due to cytotoxic and immunostimulatory pokeweed mitogen and phytolaccoside content; permitted in US cosmetics with no specific FDA ban despite documented toxicity. The EU classifies Phytolacca Decandra Extract as "prohibited". Safety rating: POOR.

Is Phytolacca Decandra Extract allowed in the EU?

Phytolacca Decandra Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Phytolacca Decandra Extract do in cosmetics?

Phytolacca Decandra Extract functions as: Pharmacologically active plant extract containing pokeweed mitogen, phytolaccosides, and pokeweed antiviral protein with cytotoxic and immunostimulatory properties. It is classified as a cosmetic ingredient in our database. CAS number: 85085-78-7 (reported).

What is the Margin of Safety for Phytolacca Decandra Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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