Pilocarpus Microphyllus Leaf Extract

INCI: PILOCARPUS MICROPHYLLUS LEAF EXTRACT

CAS Number
84604-03-5
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” general cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains pilocarpine, a potent cholinergic alkaloid with pharmacological activity; dermally absorbed pilocarpine can cause miosis, salivation, and sweating; concentration must be strictly controlled due to borderline cosmetic/pharmaceutical classification risk.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Pilocarpus Microphyllus Leaf Extract safe in cosmetics?

Contains pilocarpine, a potent cholinergic alkaloid with pharmacological activity; dermally absorbed pilocarpine can cause miosis, salivation, and sweating; concentration must be strictly controlled due to borderline cosmetic/pharmaceutical classification risk. The EU classifies Pilocarpus Microphyllus Leaf Extract as "permitted". Safety rating: MODERATE.

Is Pilocarpus Microphyllus Leaf Extract allowed in the EU?

Pilocarpus Microphyllus Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pilocarpus Microphyllus Leaf Extract do in cosmetics?

Pilocarpus Microphyllus Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84604-03-5.

What is the Margin of Safety for Pilocarpus Microphyllus Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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