Pluchea Indica Leaf Extract

INCI: PLUCHEA INDICA LEAF EXTRACT

CAS Number
Not commonly assigned
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction; no CIR assessment published

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Asteraceae/Compositae family member requiring mandatory allergen screening for sesquiterpene lactone sensitivity; cytotoxic activity documented at low in vitro concentrations; recommend cosmetic use at โ‰ค0.5% with genotoxicity data before CPSR submission.

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Pluchea Indica Leaf Extract safe in cosmetics?

Asteraceae/Compositae family member requiring mandatory allergen screening for sesquiterpene lactone sensitivity; cytotoxic activity documented at low in vitro concentrations; recommend cosmetic use at โ‰ค0.5% with genotoxicity data before CPSR submission. The EU classifies Pluchea Indica Leaf Extract as "permitted". Safety rating: MODERATE.

Is Pluchea Indica Leaf Extract allowed in the EU?

Pluchea Indica Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pluchea Indica Leaf Extract do in cosmetics?

Pluchea Indica Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not commonly assigned.

What is the Margin of Safety for Pluchea Indica Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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