Poly(1,4-Butanediol)-6

INCI: POLY(1,4-BUTANEDIOL)-6

CAS Number
25190-06-1 (parent PTMEG)
Function
Skin conditioning, emollient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA restriction; no individual CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Molecular weight below 500 Da threshold requires dermal absorption data per SCCS Notes of Guidance; residual monomer risk is elevated in short-chain variants.

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Concern Level: Moderate

Frequently Asked Questions

Is Poly(1,4-Butanediol)-6 safe in cosmetics?

Molecular weight below 500 Da threshold requires dermal absorption data per SCCS Notes of Guidance; residual monomer risk is elevated in short-chain variants. The EU classifies Poly(1,4-Butanediol)-6 as "permitted". Safety rating: MODERATE.

Is Poly(1,4-Butanediol)-6 allowed in the EU?

Poly(1,4-Butanediol)-6 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poly(1,4-Butanediol)-6 do in cosmetics?

Poly(1,4-Butanediol)-6 functions as: Skin conditioning, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 25190-06-1 (parent PTMEG).

What is the Margin of Safety for Poly(1,4-Butanediol)-6?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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