Good Emulsifier

Polyglyceryl-2 Dipolyhydroxystearate

INCI: POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE

CAS Number
144470-58-6
Function
Non-ionic W/O emulsifier, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR safe as used (274-ingredient polyglyceryl class review, 2016/2023). FDA food additive 21 CFR 172.854.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Plant-derived W/O emulsifier with high molecular weight and low dermal penetration. CIR concluded safe with no adverse effects in chronic, reproductive, or genotoxicity studies. COSMOS-eligible.

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Concern Level: Low

Regulatory Flags

eu_children_restricted

Frequently Asked Questions

Is Polyglyceryl-2 Dipolyhydroxystearate safe in cosmetics?

Plant-derived W/O emulsifier with high molecular weight and low dermal penetration. CIR concluded safe with no adverse effects in chronic, reproductive, or genotoxicity studies. COSMOS-eligible. The EU classifies Polyglyceryl-2 Dipolyhydroxystearate as "permitted". Safety rating: GOOD.

Is Polyglyceryl-2 Dipolyhydroxystearate allowed in the EU?

Polyglyceryl-2 Dipolyhydroxystearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-2 Dipolyhydroxystearate do in cosmetics?

Polyglyceryl-2 Dipolyhydroxystearate functions as: Non-ionic W/O emulsifier, skin conditioning. It is classified as a Emulsifier in our database. CAS number: 144470-58-6.

What is the Margin of Safety for Polyglyceryl-2 Dipolyhydroxystearate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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Is Polyglyceryl-2 Dipolyhydroxystearate in Your Products?

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