Excellent Emulsifier NOAEL Data

Cetearyl Olivate

Also known as: Octadecanoic acid, octadecyl ester, 1-Octadecyl octadecanoate, Amleps SS, Amreps SS, Brian DPS 60 (+15 more)

INCI: CETEARYL OLIVATE

Cetearyl Olivate (CAS 2778-96-3) is a cosmetic emulsifier functioning as emulsifier. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 2778-96-3 →

Auto-generated CPSR Part A draft with source citations
Function
emulsifier
Safety Rating
EXCELLENT

Chemistry & Identifiers

EC Number
220-476-5

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes None

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Cetearyl Olivate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Cetearyl Olivate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Cetearyl Olivate across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

4 property records from structured ingredient metadata.

baby_pediatric
{"cas_number": "124046-50-0", "ingredient_class": "emulsifier_baby_safe", "pediatric_safety_rating": "excellent", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "Olive-derived, biomimetic, lamellar structure supports barrier", "transepidermal_absorption_risk_pediatric": "very_low", "dose_per_kg_body_weight_concern": "Minima…
emulsion_hlb
{"hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.28-0.40", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "sorbitan_olivate", "optimal_oil_phase_pct": "10-28", "optimal_water_phase_pct": "72-90", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "4.0-9.5", "viscosity_building_contribution": "moder…
regulatory
{"eu_status": "allowed", "us_status": "allowed"}
synergy
{"inci_name_2": "Sorbitan Olivate", "synergy_type": "stability-enhancement", "synergy_description": "Natural olive-derived emulsifier system (Olivem 1000)", "combined_benefit": "Biomimetic liquid crystal structure, enhanced skin feel, natural-derived, stable emulsions", "efficacy_multiplier": "2.5x", "mechanism_of_action": "Forms lamellar gel network mimicking skin lipid structure for enhanced pen…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Humectant Lubricating agent Softener and conditioner Thickening agent Viscosity modifier
Regulatory List Membership (1)
FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for Cetearyl Olivate.

Regulatory Flags

peg-free cosmos-eligible ecocert-approved liquid-crystal-former biomimetic olive-derived

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Cetearyl Olivate by CAS number or substance name.

Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Octadecanoic acid, octadecyl ester 1-Octadecyl octadecanoate Amleps SS Amreps SS Brian DPS 60 Cosmol 1000 Cyclochem SS Emalex CC 18 Exceparl SS FE 78-18 Lexol SS Loxiol G 30 NJLUB SS Nissan Electol WEP 2 Nissan Unister 9676M Nissan Unister M 9676 Nissan Unister M 9796 Octadecyl octadecanoate Octadecyl stearate Radia 7501

Chemical Function

Softener and conditioner Viscosity modifier Humectant Thickening agent Lubricating agent

Regulatory Lists

Indirect additives food contact (10/2018)

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Cetearyl Olivate safe in cosmetics?

Cetearyl Olivate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Cetearyl Olivate allowed in the EU?

Cetearyl Olivate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cetearyl Olivate do in cosmetics?

Cetearyl Olivate functions as: emulsifier. It is classified as a Emulsifier in our database. CAS number: 2778-96-3.

What is the NOAEL for Cetearyl Olivate?

The NOAEL (No Observed Adverse Effect Level) for Cetearyl Olivate is =1000 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Cetearyl Olivate used outside cosmetics?

Cetearyl Olivate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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