Excellent Emulsifier Sensitization Data

Cetearyl Glucoside

INCI: CETEARYL GLUCOSIDE

Cetearyl Glucoside (CAS 246159-33-1) is a cosmetic emulsifier functioning as emulsifier. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 246159-33-1 →

Auto-generated CPSR Part A draft with source citations
Function
emulsifier
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
C25H22FN3O4
MW
447.5 g/mol
PubChem CID
168010200
IUPAC Name
7-fluoro-18-hydroxy-2-phenyl-9-oxa-1,15,22-triazatetracyclo[13.7.1.03,8.017,22]tricosa-3(8),4,6,11,17,20-hexaene-16,19-dione
InChIKey
NQIYJKJWNGOVCZ-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR (2013) assessed alkyl glucosides as safe when formulated to be non-irritating. 477 formulations reported.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Cetearyl Glucoside.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Cetearyl Glucoside based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
surfactant
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
glucoside-group
Reaction Type
contact-dermatitis

Source: NACDG; IVDK; ESSCA

Additional Ingredient Properties

7 property records from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "surfactant", "cross_reactivity_group": "glucoside-group", "patch_test_frequency_pct": "0.3", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "NACDG; IVDK; ESSCA"}
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "0", "skin_type_suitability": "all,sensitive,combination,normal,acne-prone,rosacea", "acne_safe": "yes", "source": "Natural emulsifier"}
emulsifier
{"cas_number": "111047-08-0", "ingredient_class": "O/W_emulsifier,liquid_crystal_former", "chemical_type": "alkyl_polyglucoside", "HLB_value": "11.0", "HLB_required_for_oil_phase": "10-12", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "1-3", "critical_micelle_concentration_pct": "0.01-0.05", "surface_tension_reduction_mN_m": "31", "interfacial_tension_reduction": "35", "foam_formatio…
emulsion_hlb
{"hlb_value": "11.0", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.30-0.45", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "cetearyl_alcohol", "optimal_oil_phase_pct": "10-25", "optimal_water_phase_pct": "75-90", "electrolyte_tolerance": "high", "pH_emulsion_stability_range": "3.0-10.0", "viscosity_building_con…
self_tanning
{"cas_number": "246159-33-1", "ingredient_class": "other", "tanning_mechanism": "other", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "0", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "AGE_formation_concern": …
surfactant
{"cas_number": "142980-102-2", "surfactant_type": "nonionic", "chemical_class": "glucoside", "charge_at_use_ph": "neutral", "cmc_critical_micelle_concentration_mm": "0.15377803220231367", "hlb_value": "11.88289086921636", "foam_volume_ml_ross_miles": "122", "foam_quality": "light", "foam_stability_5min_pct": "82", "cleansing_power_rating_1_to_10": "7.024304369086524", "oil_emulsification_capacity"…
synergy
{"inci_name_2": "Cetearyl Alcohol", "synergy_type": "stability-enhancement", "synergy_description": "Natural glucose-based emulsifier with fatty alcohol (Montanov 68)", "combined_benefit": "Natural emulsification, liquid crystal formation, enhanced skin feel, stable", "efficacy_multiplier": "2.5x", "mechanism_of_action": "Glucoside emulsifies; cetearyl alcohol forms lamellar gel network for biomim…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Emulsifier Surfactant (surface active agent)
Regulatory List Membership (3)
EU Regulated in Personal Care EU Restricted for Children (Cosmetics) EPA Safer Chemical Ingredients List (SCIL)

Expert Verdict

Expert safety assessment and concern-level summary for Cetearyl Glucoside.

Regulatory Flags

peg-free cosmos-eligible alkyl-polyglucoside liquid-crystal-former ecocert-approved eu_children_restricted epa_safer_alternative

Chemical Function

Surfactant (surface active agent) Emulsifier

Regulatory Lists

children; Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care SCIL (9/2019)

Australian Status

AICIS status: listed_with_terms

Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the introduction volume of the chemical exceeds 1...

Frequently Asked Questions

Is Cetearyl Glucoside safe in cosmetics?

Cetearyl Glucoside has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Cetearyl Glucoside allowed in the EU?

Cetearyl Glucoside EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cetearyl Glucoside do in cosmetics?

Cetearyl Glucoside functions as: emulsifier. It is classified as a Emulsifier in our database. CAS number: 246159-33-1.

Is Cetearyl Glucoside in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cetearyl Glucoside in your formulation.