Is Polypeptide-1 safe in cosmetics?
Polypeptide-1 has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Polypeptide-1
INCI: POLYPEPTIDE-1
Polypeptide-1 is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted.
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Synthetic peptide of 153 amino acids; no specific FDA restrictions; CIR tissue-derived protein assessment supports safety
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polypeptide-1.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Polypeptide-1.
Regulatory Flags
synthetic-peptide
skin-conditioning
anti-aging
Frequently Asked Questions
Is Polypeptide-1 allowed in the EU?
Polypeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polypeptide-1 do in cosmetics?
Polypeptide-1 functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database.
Compliance Tools
Check Polypeptide-1 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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