Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Potassium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 2000 mg/kg bw/day | oral | sheep | Short Term Toxicity | COSMOS_DB |
| NOAEL | 5250 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 195 mg/kg bw/day | oral | dog | Short Term Toxicity | COSMOS_DB |
| NOAEL | 235 mg/kg bw/day | oral | mouse | Developmental | COSMOS_DB |
| NOAEL | 310 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 1811 mg/kg bw/day | oral | cattle | Short Term Toxicity | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 1454 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 2229 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1551 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
No significant safety concerns at cosmetic-use concentrations; may cause mild stinging on broken or abraded skin due to osmotic effect.
Regulatory Flags
Frequently Asked Questions
Is Potassium Chloride safe in cosmetics?
No significant safety concerns at cosmetic-use concentrations; may cause mild stinging on broken or abraded skin due to osmotic effect. The EU classifies Potassium Chloride as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Potassium Chloride allowed in the EU?
Potassium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Potassium Chloride do in cosmetics?
Potassium Chloride functions as: Viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 7447-40-7.
What is the Margin of Safety for Potassium Chloride?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Potassium Chloride?
The NOAEL (No Observed Adverse Effect Level) for Potassium Chloride is 2000 mg/kg bw/day based on a Short Term Toxicity study via oral route in sheep. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check Potassium Chloride compliance across multiple jurisdictions:
Related Ingredients
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