Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for PPG-33 Butyl Ether. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 other | oral | rat | oral | REACH |
| NOEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 other | oral | rat | oral | REACH |
| NOAEL | 1000 other | oral | rat | oral | REACH |
Expert Verdict
No ethoxylation (PPG-only, no PEG segment) = no 1,4-dioxane concern; propylene oxide residuals possible but expected to be minimal
Regulatory Flags
Frequently Asked Questions
Is PPG-33 Butyl Ether safe in cosmetics?
No ethoxylation (PPG-only, no PEG segment) = no 1,4-dioxane concern; propylene oxide residuals possible but expected to be minimal The EU classifies PPG-33 Butyl Ether as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.
Is PPG-33 Butyl Ether allowed in the EU?
PPG-33 Butyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PPG-33 Butyl Ether do in cosmetics?
PPG-33 Butyl Ether functions as: Hair conditioning, Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 9003-13-8.
What is the Margin of Safety for PPG-33 Butyl Ether?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for PPG-33 Butyl Ether?
The NOAEL (No Observed Adverse Effect Level) for PPG-33 Butyl Ether is 1000 other based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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