Is PQQ (Pyrroloquinoline Quinone) safe in cosmetics?
PQQ (Pyrroloquinoline Quinone) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Antioxidant
PQQ (Pyrroloquinoline Quinone)
INCI: PYRROLOQUINOLINE QUINONE
PQQ (Pyrroloquinoline Quinone) (CAS None) is a cosmetic antioxidant functioning as Potent antioxidant and anti-aging active. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS None →
Auto-generated CPSR Part A draft with source citations
Function
Potent antioxidant and anti-aging active
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for PQQ (Pyrroloquinoline Quinone).
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for PQQ (Pyrroloquinoline Quinone).
Frequently Asked Questions
Is PQQ (Pyrroloquinoline Quinone) allowed in the EU?
PQQ (Pyrroloquinoline Quinone) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PQQ (Pyrroloquinoline Quinone) do in cosmetics?
PQQ (Pyrroloquinoline Quinone) functions as: Potent antioxidant and anti-aging active. It is classified as a Antioxidant in our database. CAS number: None.
Compliance Tools
Check PQQ (Pyrroloquinoline Quinone) compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Ascorbic Acid
Excellent
Same category
Antioxidant; ROS scavenger; vitamin E...
Ascorbic Acid (Vitamin C)
Excellent
Same category
Antioxidant, skin brightening
Ascorbyl Palmitate
Excellent
Same category
Lipophilic antioxidant; ester of asco...
Astaxanthin
Excellent
Same category
Antioxidant; carotenoid; singlet oxyg...
Beta-Carotene Safety Data
Excellent
Same category
Antioxidant
Catalase
Excellent
Same category
Enzymatic antioxidant; preventive ant...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
PRASTERONE
Moderate
Browse nearby
Skin Conditioning
PRIMULA VERIS FLOWER EXTRACT
Good
Browse nearby
Skin Conditioning
PROPOLIS WAX
Good
Browse nearby
Skin Conditioning, Skin Conditioning ...
Is PQQ (Pyrroloquinoline Quinone) in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for PQQ (Pyrroloquinoline Quinone) in your formulation.