Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Prenol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 82.1 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
IFRA compliance required for fragrance use; unsaturated alcohol may undergo oxidation forming sensitizing species.
Regulatory Flags
Frequently Asked Questions
Is Prenol safe in cosmetics?
IFRA compliance required for fragrance use; unsaturated alcohol may undergo oxidation forming sensitizing species. The EU classifies Prenol as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Prenol allowed in the EU?
Prenol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Prenol do in cosmetics?
Prenol functions as: Fragrance ingredient; 3-methyl-2-buten-1-ol used as aroma chemical. It is classified as a cosmetic ingredient in our database. CAS number: 556-82-1.
What is the Margin of Safety for Prenol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Prenol?
The NOAEL (No Observed Adverse Effect Level) for Prenol is 82.1 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Is Prenol classified as hazardous under GHS?
Prenol carries a GHS signal word of "WARNING". Hazard statements: Flammable liquid and vapour Harmful if swallowed Causes skin irritation Causes serious eye irritation Harmful to aquatic life. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Compliance Tools
Check Prenol compliance across multiple jurisdictions:
Related Ingredients
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