Propylene Glycol Dicaprate

INCI: PROPYLENE GLYCOL DICAPRATE

CAS Number
53824-77-4; 56519-72-3
Function
Skin-conditioning agent (occlusive); Surfactant – emulsifying agent
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR concluded "safe as used" (originally 1999, reaffirmed 2014); also permitted as direct/secondary food additive (21 CFR 172.856)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

⚠ Penetration enhancement — enhanced absorption of heparin, thiocolchicoside, and caffeine through skin (dicaprylate/dicaprate blend). Consider co-formulated ingredient safety profiles

⚠️
Concern Level: None

Frequently Asked Questions

Is Propylene Glycol Dicaprate safe in cosmetics?

⚠ Penetration enhancement — enhanced absorption of heparin, thiocolchicoside, and caffeine through skin (dicaprylate/dicaprate blend). Consider co-formulated ingredient safety profiles The EU classifies Propylene Glycol Dicaprate as "permitted". Safety rating: EXCELLENT.

Is Propylene Glycol Dicaprate allowed in the EU?

Propylene Glycol Dicaprate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propylene Glycol Dicaprate do in cosmetics?

Propylene Glycol Dicaprate functions as: Skin-conditioning agent (occlusive); Surfactant – emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 53824-77-4; 56519-72-3.

What is the Margin of Safety for Propylene Glycol Dicaprate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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