Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Punica Granatum Sterols. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=8.1 other | oral | rat | oral | REACH |
| NOAEL | 5000 ppm | oral | rat | oral | REACH |
| NOEL | 1000 ppm | oral | rat | oral | REACH |
Expert Verdict
White to light yellow waxy paste; oil-soluble; 88.70% biodegradable; derived from cold-pressed seed oil fractionation; ensure sterol fraction is free of residual solvent if further processing is applied
Frequently Asked Questions
Is Punica Granatum Sterols safe in cosmetics?
White to light yellow waxy paste; oil-soluble; 88.70% biodegradable; derived from cold-pressed seed oil fractionation; ensure sterol fraction is free of residual solvent if further processing is applied The EU classifies Punica Granatum Sterols as "permitted". Safety rating: EXCELLENT. 3 toxicological study endpoint(s) are available in our database.
Is Punica Granatum Sterols allowed in the EU?
Punica Granatum Sterols EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Punica Granatum Sterols do in cosmetics?
Punica Granatum Sterols functions as: Skin conditioning agent; hair conditioning agent; barrier function enhancement. It is classified as a cosmetic ingredient in our database. CAS number: 949109-75-5.
What is the Margin of Safety for Punica Granatum Sterols?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Punica Granatum Sterols?
The NOAEL (No Observed Adverse Effect Level) for Punica Granatum Sterols is >=8.1 other based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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