Quassin

INCI: QUASSIN

CAS Number
76-78-8 [^1_4]
Function
Denaturant, Skin Conditioning [^1_2]
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Recognized as GRAS flavoring agent (related FEMA listing); no specific cosmetic prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

H302 — harmful if swallowed; H312 — harmful in skin contact; H319 — causes serious eye irritation; H332 — harmful if inhaled [^1_5][^1_6]. Extremely bitter terpenoid.

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Concern Level: Moderate

Frequently Asked Questions

Is Quassin safe in cosmetics?

H302 — harmful if swallowed; H312 — harmful in skin contact; H319 — causes serious eye irritation; H332 — harmful if inhaled [^1_5][^1_6]. Extremely bitter terpenoid. The EU classifies Quassin as "permitted". Safety rating: MODERATE.

Is Quassin allowed in the EU?

Quassin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Quassin do in cosmetics?

Quassin functions as: Denaturant, Skin Conditioning [^1_2]. It is classified as a cosmetic ingredient in our database. CAS number: 76-78-8 [^1_4].

What is the Margin of Safety for Quassin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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