Rice RH-Oligopeptide-2

INCI: RICE RH-OLIGOPEPTIDE-2

CAS Number
67763-96-6 (for parent rh-Oligopeptide-2 / IGF-1 analog); 52500-60-4 also referenced [^1_5]
Function
Skin Conditioning (IGF-1 / Insulin-like Growth Factor 1 analog) [^1_6]
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted; permitted under general cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

As an IGF-1 analog, theoretical concerns about promoting cell proliferation exist; should be used at low concentrations; limited independent toxicological data for the rice-expressed form [^1_6]

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Concern Level: High

Frequently Asked Questions

Is Rice RH-Oligopeptide-2 safe in cosmetics?

As an IGF-1 analog, theoretical concerns about promoting cell proliferation exist; should be used at low concentrations; limited independent toxicological data for the rice-expressed form [^1_6] The EU classifies Rice RH-Oligopeptide-2 as "permitted". Safety rating: MODERATE.

Is Rice RH-Oligopeptide-2 allowed in the EU?

Rice RH-Oligopeptide-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rice RH-Oligopeptide-2 do in cosmetics?

Rice RH-Oligopeptide-2 functions as: Skin Conditioning (IGF-1 / Insulin-like Growth Factor 1 analog) [^1_6]. It is classified as a cosmetic ingredient in our database. CAS number: 67763-96-6 (for parent rh-Oligopeptide-2 / IGF-1 analog); 52500-60-4 also referenced [^1_5].

What is the Margin of Safety for Rice RH-Oligopeptide-2?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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