Rice SH-Oligopeptide-2

INCI: RICE SH-OLIGOPEPTIDE-2

CAS Number
Not specifically assigned for rice variant (IGF-1 analog)
Function
Skin Conditioning — IGF-1 analog
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes Not specifically restricted; permitted under general cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Overlapping function with ingredient \#2 (both IGF-1 analogs); theoretical proliferative risk at high concentrations; use at typical cosmetic levels (ppm range) considered safe by suppliers

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Concern Level: Moderate

Frequently Asked Questions

Is Rice SH-Oligopeptide-2 safe in cosmetics?

Overlapping function with ingredient \#2 (both IGF-1 analogs); theoretical proliferative risk at high concentrations; use at typical cosmetic levels (ppm range) considered safe by suppliers The EU classifies Rice SH-Oligopeptide-2 as "permitted". Safety rating: MODERATE.

Is Rice SH-Oligopeptide-2 allowed in the EU?

Rice SH-Oligopeptide-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rice SH-Oligopeptide-2 do in cosmetics?

Rice SH-Oligopeptide-2 functions as: Skin Conditioning — IGF-1 analog. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned for rice variant (IGF-1 analog).

What is the Margin of Safety for Rice SH-Oligopeptide-2?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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