Moderate Cosmetic Ingredient NOAEL Data GHS Classified

Rosin

INCI: ROSIN

CAS Number
8050-09-7
Function
Film forming, binding, depilatory, viscosity controlling, perfuming
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; used in VCRP-listed products

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Rosin. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL ca.10 mg/kg bw/day oral rat oral REACH
NOAEL ca.10 mg/kg bw/day oral rat oral REACH
NOAEL ca.10 mg/kg bw/day oral - oral REACH
NOAEL 0.2 other oral rat oral REACH
NOAEL 0.05 other oral rat oral REACH
NOAEL 4000 ppm oral dog oral REACH
NOAEL >2200 mg/kg bw/day oral rat oral REACH
NOAEL 1 other oral dog oral REACH
NOAEL 316 mg/kg bw/day oral rat oral REACH
NOEL 1000 ppm oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Long-term Exposure Effects
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma.
Routes of Exposure
The substance can be absorbed into the body by inhalation of fume.

Expert Verdict

One of the most common contact allergens worldwide; cross-reactivity with modified rosins and rosin derivatives; contraindicated for sensitized individuals

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component fda_food_additive

Frequently Asked Questions

Is Rosin safe in cosmetics?

One of the most common contact allergens worldwide; cross-reactivity with modified rosins and rosin derivatives; contraindicated for sensitized individuals The EU classifies Rosin as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.

Is Rosin allowed in the EU?

Rosin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rosin do in cosmetics?

Rosin functions as: Film forming, binding, depilatory, viscosity controlling, perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 8050-09-7.

What is the Margin of Safety for Rosin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Rosin?

The NOAEL (No Observed Adverse Effect Level) for Rosin is ca.10 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.

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