Moderate Cosmetic Ingredient NOAEL Data

Rosmarinus Officinalis Flower Cera

INCI: ROSMARINUS OFFICINALIS FLOWER CERA

CAS Number
84604-14-8
Function
Skin conditioning agent (emollient/occlusive wax)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not separately listed; rosemary is GRAS (21CFR182.10). No specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

8 study endpoints found for Rosmarinus Officinalis Flower Cera. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 200 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 130 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 130 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 1500 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
dose_tested 200 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
dose_tested 130 mg/kg bw/day oral rat Developmental COSMOS_DB
dose_tested 130 mg/kg bw/day oral rat Developmental COSMOS_DB
dose_tested 1500 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Expert Verdict

Excluded from CIR monograph โ€” no peer-reviewed safety conclusion exists. Must be self-assessed by manufacturer. Contains allergen terpenes. Essentially identical concern applies to "Flower Wax"

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Concern Level: Moderate

Regulatory Flags

potential-allergen eu_children_restricted fda_food_additive

Frequently Asked Questions

Is Rosmarinus Officinalis Flower Cera safe in cosmetics?

Excluded from CIR monograph โ€” no peer-reviewed safety conclusion exists. Must be self-assessed by manufacturer. Contains allergen terpenes. Essentially identical concern applies to "Flower Wax" The EU classifies Rosmarinus Officinalis Flower Cera as "restricted". Safety rating: MODERATE. 8 toxicological study endpoint(s) are available in our database.

Is Rosmarinus Officinalis Flower Cera allowed in the EU?

Rosmarinus Officinalis Flower Cera EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rosmarinus Officinalis Flower Cera do in cosmetics?

Rosmarinus Officinalis Flower Cera functions as: Skin conditioning agent (emollient/occlusive wax). It is classified as a cosmetic ingredient in our database. CAS number: 84604-14-8.

What is the Margin of Safety for Rosmarinus Officinalis Flower Cera?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Rosmarinus Officinalis Flower Cera?

The NOAEL (No Observed Adverse Effect Level) for Rosmarinus Officinalis Flower Cera is 200 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 8 study endpoints are available. Source: COSMOS_DB.

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