Rosmarinus Officinalis Stem Oil
INCI: ROSMARINUS OFFICINALIS (ROSEMARY) STEM OIL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for Rosmarinus Officinalis Stem Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 200 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 130 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 130 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| dose_tested | 200 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| dose_tested | 130 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| dose_tested | 130 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| dose_tested | 1500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Contains camphor and 1,8-cineole (potential neurotoxicity at high doses); not suitable for products intended for infants/children; oxidized terpenes increase sensitization risk
Regulatory Flags
Frequently Asked Questions
Is Rosmarinus Officinalis Stem Oil safe in cosmetics?
Contains camphor and 1,8-cineole (potential neurotoxicity at high doses); not suitable for products intended for infants/children; oxidized terpenes increase sensitization risk The EU classifies Rosmarinus Officinalis Stem Oil as "permitted". Safety rating: MODERATE. 8 toxicological study endpoint(s) are available in our database.
Is Rosmarinus Officinalis Stem Oil allowed in the EU?
Rosmarinus Officinalis Stem Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Rosmarinus Officinalis Stem Oil do in cosmetics?
Rosmarinus Officinalis Stem Oil functions as: Fragrance, tonic, stimulant, masking. It is classified as a cosmetic ingredient in our database. CAS number: 84604-14-8.
What is the Margin of Safety for Rosmarinus Officinalis Stem Oil?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Rosmarinus Officinalis Stem Oil?
The NOAEL (No Observed Adverse Effect Level) for Rosmarinus Officinalis Stem Oil is 200 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 8 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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