Is Rubber Latex safe in cosmetics?
Rubber Latex has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
Poor
Cosmetic Ingredient
Rubber Latex
Also known as: Rubber, Caoutchouc, EINECS 232-689-0, Latex gum, Latex particles (+5 more)
INCI: RUBBER LATEX
Rubber Latex (CAS 9006-04-6) is a cosmetic cosmetic ingredient functioning as Film forming, viscosity controlling, binding agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 9006-04-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Rubber Latex is classified GHS Danger (H224, H320, H336, H341, H351, H372, H335, H350) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Film forming, viscosity controlling, binding agent
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
2-methylbuta-1,3-diene
InChIKey
RRHGJUQNOFWUDK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FDA has issued specific guidance on latex in cosmetics due to allergenic risk
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Rubber Latex.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CA | restricted | Notification to Cosmetics Division required | All latex-containing cosmetics |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (7)
Carcinogen Classification
Isoprene | Group 2B: Possibly carcinogenic to humans | Volume 60: (1994) Some Industrial Chemicals | Volume 71: (1999) Re-evaluation of Some Organic Chemicals, Hydrazine and Hydrogen Peroxide (Part 1, Part 2, Part 3)
Source: International Agency for Research on Cancer (IARC)
Carcinogen Classification
Isoprene | TR-486: Toxicology and Carcinogenesis Studies of Isoprene (CASRN 78-79-5) in F344/N Rats (Inhalation Studies) (1999 ) | 12/10/97 | Clear Evidence | Some Evidence | Chemical Not Tested in Species/Sex | Chemical Not Tested in Species/Sex | Under the conditions of this 2-year inhalation study, there was clear evidence of carcinogenic activity of isoprene in male F344/N rats based
Source: NTP Technical Reports
Evidence for Carcinogenicity
Evaluation: No epidemiological data relevant to the carcinogenicity of isoprene were available. There is sufficient evidence in experimental animals for the carcinogenicity of isoprene. Overall evaluation: Isoprene is possibly carcinogenic to humans (Group 2B). | Isoprene is reasonably anticipated to be a human carcinogen
Source: Hazardous Substances Data Bank (HSDB)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
ICSC Safety Card
0904
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Filler
Film former
Flavouring and nutrient
Opacifer
Regulatory List Membership (2)
FDA Substances Added to Food (EAFUS)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Rubber Latex.
Regulatory Flags
potential-allergen
fda_food_additive
Known Synonyms
Rubber
Caoutchouc
EINECS 232-689-0
Latex gum
Latex particles
Nafka kristalgom
Natural latex
Polyisoprene
Thiokol NVT
UNII-2LQ0UUW8IN
Chemical Function
Film former
Opacifer
Filler
Regulatory Lists
consumer_product; Europe
Europe; Road vehicles
Europe; Toys and children's products
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
inert_ingredient; non_food_use; Pesticides
Indirect additives food contact (10/2018)
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
4
Frequently Asked Questions
Is Rubber Latex allowed in the EU?
Rubber Latex EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Rubber Latex do in cosmetics?
Rubber Latex functions as: Film forming, viscosity controlling, binding agent. It is classified as a cosmetic ingredient in our database. CAS number: 9006-04-6.
Is Rubber Latex used outside cosmetics?
Rubber Latex also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Rubber Latex have different safety status in cosmetics vs industrial chemicals?
Rubber Latex is classified GHS Danger (H224, H320, H336, H341, H351, H372, H335, H350) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Rubber Latex compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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